How is Methamphetamine abused? Meth is taken orally, smoked, snorted or dissolved in water or alcohol and injected. Meth increases the amount of the neurotransmitter dopamine, leading to high levels of that chemical in the brain.
Dopamine is involved in reward, motivation, the experience of pleasure and motor function. Neurotransmitter dopamine release reward, pleasure, motivation, and motor function. Methamphetamine’s ability to release dopamine rapidly in reward regions of the brain produces the euphoric rush or flashes that many users experience. The long-term uses of meth are anxiety, mood disturbance, confusion, insomnia and violent behavior. Meth can be prescribed by doctors to treat attention deficit hyperactivity disorder and other conditions, although it is rarely used medicinally, and only at doses much lower than those typically abused.